At The Clifford Clinic, we offer the Tone-Up Booster, an advanced dual-formula mesotherapy solution specifically designed to address uneven skin tone, dull complexion, pigmentation, and compromised skin barrier function.
This treatment combines scientifically proven active ingredients to deliver visible results with minimal downtime. Unlike conventional brightening solutions, Tone-Up Booster simultaneously improves dermal health and skin tone by targeting both collagen regeneration and melanin suppression, making it a powerful all-in-one treatment for revitalised, radiant skin.
The Tone-Up Booster is formulated with two distinct vials that are freshly mixed before application to activate their synergistic effects. The first vial contains c-PDRN®, hyaluronic acid, and panthenol. c-PDRN® (polydeoxyribonucleotide) is a DNA fragment derived from Korean wild salmon using patented DOT™ technology, with molecules small enough—670 times smaller than the average skin pore—to be deeply absorbed into the skin.
It acts at a cellular level to promote tissue repair, stimulate collagen production, and strengthen the skin’s barrier function. Hyaluronic acid, a naturally occurring molecule in the skin, supports hydration and plumpness while protecting against free radical damage and promoting re-epithelialisation. Panthenol, or provitamin B5, further enhances hydration and soothes inflammation, helping to restore balance and comfort to stressed or damaged skin.
The second vial is a potent skin brightening and depigmentation solution composed of ascorbic acid (vitamin C), glutathione, and tranexamic acid. These ingredients are combined in precise ratios to inhibit tyrosinase activity, suppress melanin production, and reduce pigmentation over time. Ascorbic acid plays a critical role in collagen synthesis and offers strong antioxidant protection, while also helping to even out skin tone and improve moisture retention.
Glutathione, a powerful tripeptide antioxidant, regulates the shift from eumelanin to pheomelanin production, leading to a lighter, more luminous complexion. When prepared with hyaluronic acid, it also minimizes the typical sulfuric odor often associated with glutathione treatments.
Tranexamic acid, commonly used in dermatology for treating melasma and hyperpigmentation, works by inhibiting melanocyte activation pathways and has been clinically shown to effectively reduce stubborn discoloration.
The dual-action mechanism of the Tone-Up Booster makes it suitable for a wide range of skin concerns, including post-inflammatory hyperpigmentation, melasma, UV-induced dark spots, and general skin dullness.
What sets this treatment apart is its ability to enhance both the skin’s appearance and underlying health at the same time. As the active compounds work in harmony, patients can expect gradual improvement in skin tone uniformity, clarity, and elasticity, with long-lasting structural benefits such as improved collagen density and dermal resilience.
Rejuran® Tone-Up Booster at The Clifford Clinic
At The Clifford Clinic, the Tone-Up Booster is administered via Bellasonic to enhance absorption and optimise results.
The solution is prepared fresh on-site by mixing both vials, and applied using aseptic mesotherapy techniques to ensure even delivery across the treatment area. A full course generally consists of four to six sessions spaced two to four weeks apart, with maintenance every few months depending on the patient’s skin condition and aesthetic goals.
Patients often notice subtle improvements after the first session, with more significant results becoming evident after the third treatment.
Skin appears brighter, more hydrated, and noticeably clearer. In clinical studies, this treatment protocol has demonstrated improvements in skin barrier integrity, collagen synthesis, pigmentation reduction, and skin texture—all key indicators of skin vitality and youthfulness. Best of all, the treatment is non-invasive and typically involves minimal to no downtime, making it suitable for those with active lifestyles.
Tone-Up Booster is especially beneficial for individuals with sensitive skin, post-acne pigmentation, melasma-prone skin, or signs of photoaging. It is also suitable for those who have previously undergone aggressive laser treatments and are seeking to maintain or enhance their results. Because it works on both the surface and deeper dermal layers, it is an ideal solution for patients looking for natural radiance without resorting to harsh bleaching agents or intensive procedures.
At The Clifford Clinic, our aesthetic doctors are experienced in delivering skin booster treatments with precision and care.
We personalise each session based on the individual’s skin profile and objectives, using medical-grade protocols and strict safety standards to ensure optimal outcomes. Every treatment is performed under professional supervision, and our team is committed to delivering not just visible improvement, but also long-term skin health and satisfaction.
To find out if Tone-Up Booster is right for you, book a consultation with our doctors today. Experience the confidence that comes with luminous, even-toned, and youthful-looking skin—powered by clinically backed Korean biotechnology and tailored expertise from The Clifford Clinic.
