Polynucleotide Skinbooster
A Bio-stimulating Treatment That Hydrates, Antioxidizes and Promotes Skin Renewal
It is a polynucleotide-based injectable bio-stimulant that stimulates the production of collagen and elastin in the skin’s dermis; it reverses the effects of aging via promoting bio-regeneration to rejuvenate skin and combat skin laxity.
What is a Biostimulator?
Biostimulators are bio-compatible (compatible with the human body) synthetic materials that stimulate fibroblasts (collagen producing cells) in the dermis to increase collogen and elastin production, tightening and lifting the skin.
Biostimulators are commonly used as aesthetic injectables for treating problems associated with aging such as sagging due to loss of skin structure and elasticity, fine lines, wrinkles, and/or loss of skin hydration. In addition to treating the symptoms of aging, Polynucleotide Skinbooster is a versatile treatment that can also be used for:
- Correcting skin dehydration and asphyxiation
- Alleviating oxidative stress in the skin
- Treating scars (eg. chickenpox or acne scar treatment)
- Treating stretch marks
Lift, antioxidize and hydrate
Polynucleotide Skinbooster is a triple-action anti-ageing treatment that rebuilds the skin using bio-stimulation; Bio-remodelling of the skin is achieved at three levels:
- Lifting by encouraging fibroblast activity
- Antioxidant effect that neutralizes harmful free radicals in the skin
- Hydration by binding to water molecules at the cellular level
Lifting
The polynucleotides present in Polynucleotide Skinbooster are bio-engineered to stimulate receptors found on the surface of fibroblast cells in the skin’s dermis. Stimulation of these cell receptors triggers the activation of fibroblasts into type I collagen and elastin producing myofibroblast cells, which in turn firms and lifts the skin to reduce sagging and smoothen out wrinkles.
Restructuring of the dermal matrix via new collagen and elastin production ensures that the root cause of skin laxity is addressed, allowing for long-lasting and deep rejuvenation of the skin.
Antioxidant effect
Free radicals damage and break down cells over time; damaged collagen fibres and skin cells can cause deterioration in the structure and appearance of the skin, leading to loss of skin elasticity, formation of wrinkles, or a change in skin texture.
It removes free radicals by acting as a free radical scavenger; the strong antioxidant effect of Polynucleotide Skinbooster allows it to protect collagen fibres, newly rejuvenated skin, and the skin’s epidermis from further damage by free radicals.
Hydrating
Polynucleotides are the main ingredient and have a high affinity for binding with water. The binding of polynucleotides to water molecules in the dermal matrix allows for deep and lasting hydration as well as hydrolifting of the skin, giving the skin a firm and moisturized feel.
Why Choose The Clifford Clinic for Polynucleotide Skinbooster?
Trusted Experts in Collagen Stimulation
Our experienced aesthetic doctors are skilled in using injectables to activate your skin’s natural collagen production—achieving firming, lifting, and long-lasting rejuvenation without surgery.Personalised Injection Techniques
At The Clifford Clinic, treatments are customised using precise injection methods and mapping based on your facial anatomy—ensuring natural-looking enhancement with minimal risk and downtime.Comprehensive Anti-Aging Protocols
Treatments can be combined with synergistic treatments like Skinboosters, RF, or laser therapy to enhance and prolong results—providing a holistic approach to skin rejuvenation tailored to your long-term aesthetic goals.
FAQ
No, it is not a filler. Unlike injectable fillers that contain hyaluronic acid, it is a bio-stimulant that stimulates the activation of fibroblasts to induce increased collagen and elastin production.
Traditional fillers are able to hydrate and increase the “bulk” or volume of the skin but may be unsuitable for individuals with water retention problems, or unsuitable for use on certain parts of the face that are more likely to be affected by water retention or where adding significant “bulk” is undesirable (eg. The thin skin around the eyes).
Biostimulators are thus considered preferable for individuals seeking to rejuvenating and hydrate the skin without risking excessive water retention or adding significant volume to the treatment area.
It is compatible with the use of dermal fillers and can be used as a complement to volumizing treatments for better results.
After a detailed consultation with our doctors at The Clifford Clinic, a layer of numbing cream will be applied onto the area for 30 minutes prior to the injections.
5 to 7 injection points, depending on if a 5 point technique or 7 point technique is used, will be marked out on each side of the face to allow it to be injected into the dermal matrix.
- Firmer and youthful looking skin
- Improved skin elasticity and reduced sagging
- Increased collagen production for sustained skin firmness
- Improvements in the appearance of fine lines and wrinkles
Results are expected to last up to 1-2 years.
- Pregnant or breastfeeding individuals
- Patients with underlying autoimmune diseases or coagulation disorders
Each syringe contains 2mls of the product.
Our Certified Medical Doctors
Dr. Gerard Ee
Dr. Gerard Ee is the founder and medical director of The Clifford Clinic. He is fully accredited in cosmetic treatments including fillers, Botox, light therapies, and more. Driven by his passion for sharing his expertise across the medical community, Dr. Ee has accumulated his surgical experiences internationally from working in the Mount Sinai Hospital in New York, National University Hospital (NUH), and Singapore General Hospital (SGH).
Dr. Chow Yuen Ho
Dr. Chow Yuen Ho is the founder and medical director of The Clifford Clinic. With over 10 years of clinical practice experience, the reputable aesthetic doctor specializes in non-invasive aesthetic and acne treatments. Dr. Chow has accomplished so much in this field. He served as the founding Director of Medical Informatics at SGH and then as the Managing Director of the Asian division of Alert Life Sciences Computing.
Dr. Law Zhi Wei
Dr. Law is a highly experienced medical professional specializing in acne treatments and aesthetic medicine. A graduate from the National University of Singapore and a member of the Royal College of Surgeons (Edinburgh), he has comprehensive clinical experience from renowned institutions such as KKH, SGH, and CGH. Passionate about the transformative power of effective acne care, Dr. Law is fully accredited in advanced treatments including lasers, radiofrequency, ultrasound therapies, Botox, and fillers. Holding a Postgraduate Diploma in Practical Dermatology from Cardiff University, he continuously updates his expertise to provide personalised, effective acne solutions, enhancing patients’ confidence and overall well-being.