The First Injectable Liquid Polycaprolactone (PCL)
What is PCL filler?
DEXLEVO, a company from South Korea, had invented the world’s first liquid polymer filler.
PCL can be degraded by the human body and hence, its popular use as an implantable biomaterial.
PCL has been approved by the Food and Drug Administration (FDA) in specific applications used in the human body such as drug delivery device and sutures. By stimulating collagen product, PCL-based products can reverse facial ageing features such as volume loss and contour laxity, providing a good long-lasting natural effect.
PCL filler has anti-aging properties and is biodegradable as well. Being in a liquid form, the filler can spread evenly throughout the entire face and hence promotes natural skin collagen synthesis, which helps your skin age more gracefully.
PCL Fillers vs Dermal Fillers
PCL Filler is developed using DEXLEVO’s Caollagenesis-Enabled Solubilized Active and Biodegradable Polymer Technology (CESABP) technology that enables regeneration of natural skin collagen without the use of microparticles.
There are hyaluronic acid (HA)- base fillers and PCL-base fillers. Dermal fillers may also have a regenerative impact on the collagen. Due to the nature and shape of particles, dermal filler cannot be injected evenly into the skin. As a result, these fillers are limited to focal areas only. For example, we can use a PCL-based filler to fill up certain types of acne scars.
As such, PCL Filler is more for a generalized effect while dermal fillers are more targeted and focused on areas that have a specific volume defect.
PCL Filler VS Injectable Moisturizers - Hyaluronic Acid
While both PCL Filler and Injectable Moisturizers – Hyaluronic Acid only require 10 injection points, they are made of different substances. PCL Filler is made with fully solubilized liquid form of PCL while Injectable Moisturizers – Hyaluronic Acid is made from Hyaluronic Acid (HA). Injectable Moisturizers – Hyaluronic Acid can help with hydrating the skin as well as giving a gentle glow to the skin, while PCL Filler helps by giving a gentle lifting effect to the face in a generalized fashion.
Benefits of PCL Filler
- Fewer injection points, as compared to other types of skin injectables, except Injectable Moisturizers – Hyaluronic Acid which requires the same injection points
- Transforms into a three-dimensional matrix and encourages fibroblasts formation
- Stimulates new collagen production
- Increases skin elasticity and rendering a gentle facelift
Treatment Procedure
PCL Filler is carefully injected into 5 specific points on each side of the patient’s face. A layer of numbing cream will be applied prior to the procedure.
Why Choose The Clifford Clinic for the First Injectable Liquid Polycaprolactone (PCL)?
Early Adopters of Liquid PCL in Singapore
The clinic offers one of the first liquid PCL injectables available locally, with experience in its usage and integration into clinical protocols.Doctor-Performed Injections with Anatomical Precision
All injections are carried out by medical doctors trained in facial anatomy, ensuring accurate placement of the product to stimulate collagen and improve skin structure.Dual Benefit: Immediate Hydration + Long-Term Collagen Stimulation
Liquid PCL provides initial skin hydration while gradually stimulating the body’s natural collagen production over time, making it suitable for improving skin density and elasticity.Integrated with Combination Treatment Plans
The treatment can be combined with other procedures such as lasers, Skinboosters, or radiofrequency to support long-term structural improvements and maintain overall skin quality.
Our Certified Medical Doctors
Dr. Gerard Ee
Dr. Gerard Ee is the founder and medical director of The Clifford Clinic. He is fully accredited in cosmetic treatments including fillers, Botox, light therapies, and more. Driven by his passion for sharing his expertise across the medical community, Dr. Ee has accumulated his surgical experiences internationally from working in the Mount Sinai Hospital in New York, National University Hospital (NUH), and Singapore General Hospital (SGH).
Dr. Chow Yuen Ho
Dr. Chow Yuen Ho is the founder and medical director of The Clifford Clinic. With over 10 years of clinical practice experience, the reputable aesthetic doctor specializes in non-invasive aesthetic and acne treatments. Dr. Chow has accomplished so much in this field. He served as the founding Director of Medical Informatics at SGH and then as the Managing Director of the Asian division of Alert Life Sciences Computing.
Dr. Law Zhi Wei
Dr. Law is a highly experienced medical professional specializing in acne treatments and aesthetic medicine. A graduate from the National University of Singapore and a member of the Royal College of Surgeons (Edinburgh), he has comprehensive clinical experience from renowned institutions such as KKH, SGH, and CGH. Passionate about the transformative power of effective acne care, Dr. Law is fully accredited in advanced treatments including lasers, radiofrequency, ultrasound therapies, Botox, and fillers. Holding a Postgraduate Diploma in Practical Dermatology from Cardiff University, he continuously updates his expertise to provide personalised, effective acne solutions, enhancing patients’ confidence and overall well-being.
FAQ
Anyone who is interested in anti-aging and feels there is generalized volume loss on the face is suitable for PCL Filler. As everyone has unique skin condition, please consult the doctor before commencing treatment.
Typically, the first visual benefits are visible after 1-2 weeks, up till a month for some patients.
It depends on each individual. PCL generally can last for about 12 month in the body.
The current protocol recommends 3 sessions at 4 weeks interval for good results.
PCL Filler is not dissolvable.
Yes, you can supplement PCL Filler treatment with other treatments like skin boosters and Botox.